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| 2021-12-09 13:17:32 | onclick： | Researchers found an invisible version of the Omicron strain |
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"Reference News" published a report on the website of the guardian on the 9th that "scientists have found an" invisible "Omicron strain that is more difficult to track". The summary of the report is as follows:
Scientists say they have found an "invisible" strain of Omicron, which can not be distinguished from other mutant strains by common polymerase chain reaction (PCR). At present, public health officials use PCR to quickly understand its global transmission.
Many variations of the "invisible version" variant are the same as those of the ordinary Omicron strain, but lack a special genetic variation. This variant is still judged to be COVID-19 in all routine tests, and can be identified by genetic testing. It is impossible to detect potential cases by routine PCR detection.
The researchers said that it is not known whether the transmission mode of this new Omicron variant is the same as that of the ordinary Omicron variant, but the gene difference of this "invisible version" is huge, so the performance may also be different.
The "invisible version" was first discovered in the COVID-19 genome submitted by South Africa, Australia and Canada recently. 7 cases were identified, but the scope of transmission could be wider. The discovery of a new Omicron strain prompted researchers to split the b.1.1.529 lineage into ordinary Omicron strain ba. 1 and a new variant ba. 2. Fran ç OIS Barlow, director of the Institute of genetics at University College London, said: "the Omicron strain has two lineages, BA. 1 and ba. 2. There are huge genetic differences between them and their performance may also be different."
Scientists will use genome-wide analysis to determine which variants of COVID-19 infection belong to, but PCR tests can sometimes give directions. About half of the PCR instruments in the UK will look for three genes of the virus, and Omicron and the previous alpha variant strains tested positive for two of them. This is because the two strains have genetic variation of spike gene deletion.
Some researchers informally call this new variant "invisible Omicron" because it has no spike gene deletion and cannot be detected by PCR. A major unknown is how this new variant was produced. Although it still belongs to Omicron, there are huge genetic differences between them. If it spreads rapidly, it may be characterized as a new "concern mutant".
One researcher said that the successive occurrence of two variants in Omicron (BA. 1 and ba. 2) was "worrying", and said that public health monitoring "missed a large piece of the puzzle".
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