home | Website Reputation | Service Application Form
evaluation
  • Run into the paper statistics, helpless. On Qimo, I saw that Dr.Tong company provided the assistance of thesis statistics, and with the guidance and assistance of the doctor's teacher, I ran smoothly to get the results. Thank Dr.Tong for his high-level service.
    Mr. Lin
    from: tainan
  • When a doctoral dissertation encounters multiple linear regression, it has always been a difficult point and there is nothing to do. On Google, we can see that the doctor teacher of Dr.Tong statistics company provides statistical running and statistical guidance. The information and requirements to the doctor teacher, with the help of the teacher, smoothly run out the results. Thank you for the help and guidance from the doctor of Dr.Tong statistics company.
    Dr. Li
    from: taoyuan
  • When I met the difficulties in the statistical analysis of the doctoral thesis questionnaire, I couldn't find a clue. Finally, I saw Dr.Tong's assistance in the statistical analysis of the thesis questionnaire on qimo.com. With the assistance of the doctor, I got the results smoothly. Thank Dr.Tong for his assistance in the statistical analysis of the thesis questionnaire, which solved my urgent problem.
    Dr. Li
    from: Kaohsiung
  • Previously, a local statistics company in Hong Kong was entrusted, but it failed to do a good job in medical statistics. In my anxiety, I saw the doctor teacher of Dr.Tong statistics company provide statistical running and guidance, and sent the data and requirements to the doctor teacher. With the efforts of the doctor teacher, the analysis results were successfully made. I feel that Taiwan's statistics companies are more professional and the fees are reasonable.
    Dr. Li
    from: hongkong
  • Thank you for the efficient and high quality service provided by the doctor teacher of Dr.Tong statistics company. Solved my urgent need.
    Mr. Lin
    from: yunlin
  • When I met the difficulties in the statistical analysis of the pre-test and post-test of the thesis questionnaire, I couldn't solve them all the time. On Qimo, I saw that the doctoral teacher of Dr.Tong statistics company provided the tutoring service of thesis statistics, and sent the information and requirements to the doctoral teacher. With the help and guidance of the teacher, I got the results. Thank you very much for the tutoring service of the doctoral teacher of Dr.Tong statistics company There are two difficulties.
    Miss Liu
    from: Kaohsiung
  • It is difficult to analyze English papers by SPSS. On Google, we can see that the doctoral teacher of Dr.Tong statistics company provides the paper statistics running and guidance, sends the data and analysis requirements to the teacher, communicates with the teacher, and runs smoothly with the teacher's guidance and help. Thank you very much for the help of the doctor teacher of Dr.Tong statistics company. The teacher is serious, responsible and powerful.
    Miss Zeng
    from: london
  • It's difficult to analyze Stata data in accounting papers. On Yahoo Qimo, I saw the doctor teacher of Dr.Tong statistics company provide Stata statistical running guidance. The data and requirements were sent to the doctor's teacher. Under the guidance of the doctor's teacher, the Stata code was successfully designed, and the analysis results were also run out. I would like to thank the doctor's teacher of Dr.Tong statistics for his high level guidance and assistance.
    Mr. Zhang
    from: taizhong
  • Educational papers have quantitative statistics, which is a bit difficult! Helpless, I saw on Yahoo Qimo that Dr. and postdoctoral teachers from Dr.Tong Statistics Company provide doctoral thesis statistics and counseling services. I sent the questionnaire and sample data to the doctor, and with the guidance and assistance of the doctor, I successfully obtained the results and graduated. I am very grateful for the professional guidance of the doctor and postdoctoral teacher from Dr.Tong Statistics Company. The technical expertise, reliable quality, and reasonable fees have saved me a lot of trouble.
    Dr. Song
    from: Kaohsiung
2021-08-13 13:16:53 | onclick: | Effects of thousands of rare protein coding genetic variations on diseases

According to the information from 280000 volunteers in the British biological sample bank, a genetics paper published in the British journal Nature on the 12th clarified the impact of thousands of rare protein coding genetic variations on diseases. This study may contribute to the understanding of diseases and the development of new drugs.

Genome wide association research has found thousands of common variants related to human diseases. It can be said that the research on the impact of these common gene variants on health and diseases has been relatively sufficient. However, there has been little research on rare variants in the scientific community, so people know less about them.

A great opportunity to study these rare variants is the large biomedical database. Among them, the British biological sample bank contains medical and genetic data of more than 500000 people (at the time of recruitment), and its resources are very helpful to study the genetic basis of health and disease. The largest data set contained in the biological sample database is genotype and brain scanning. These resources are conducive to the study of genes affecting human structure and function.

This time, the team led by AstraZeneca researchers in the UK used the whole exon sequencing data of 281104 biological sample bank volunteers to evaluate the relationship between rare protein coding variants and more than 18500 complex phenotypes (such as asthma and other diseases affected by multiple genetic and environmental factors). They identified correlations at the level of 46837 variants and 1703 genes, including previously unknown associations.

The researchers said that some gene phenotype associations in the results are considered to have the potential to become new targets for drug intervention.

However, although about 12000 volunteers in this study have genetic ancestors from Africa, East Asia and South Asia, most of the samples are volunteers of European descent, which means that the diversity construction of biological sample bank needs to be strengthened.

British biological sample bank is a 30-year large-scale scientific research initiated by the British government. It is also one of the largest and most ambitious health research projects in the UK. Its goal is to build the world's largest information resource bank on genes and environmental factors that cause or prevent diseases, and explore the relationship between human specific genes, lifestyle and health status, Improve understanding of some genetic diseases, including cancer, heart disease, diabetes and mental illness.

  Leave a message
Email: *
Phone: *
Verification Code:
  Latest message
[ LIST | TOP ]