Recently, Alexander Semyonov, director of the Yekaterinburg branch of the national vector Science Center for Virology and biotechnology, said that unlike coronavirus or hepatitis B virus, coronavirus is not a virus that can be embedded in the human genome. They do not have genes encoding proteins to cut human DNA. The virus was embedded in chromosome; Coronavirus is constantly mutating, and the mutation process is developing towards the direction of increasing infectivity. Each mutant strain is more infectious and aggressive than before, which is the law of natural selection.

The representative of coronavirus, the coronavirus family, does not have the necessary structure to integrate with the human genome and to intervene in it artificially, said Mr. Xie. There are indeed viruses that can be inserted into the human genome in nature, such as HIV, hepatitis B virus, various tumor viruses, which scientists have already studied. But the coronavirus family can not embed the genome at all. They have no genes encoding proteins to cut human DNA and embed the virus into the chromosome.

According to symonov, coronavirus is constantly mutating and the mutation process is developing towards increasing infectivity. Each mutant is more infectious and aggressive than the previous one, which is the law of natural selection. For example, the third wave caused by the delta mutant strain is obviously more infectious than the original COVID-19, Alfa mutant strain and beta variant strain, and has been spread all over the world, replacing the other variant strains of COVID-19. Many experts in the world also believe that delta is significantly different from other variant strains, and that from the perspective of infection, delta is moving towards a "worse" direction.

Alexander symonov said it is more suitable for penetration into human cells, reproducing faster, attacking more tissues, including lung tissue, and infecting young people due to some mutations in the delta virus genome. Patients infected with delta virus base have symptoms more like acute respiratory virus infection, runny nose, sore throat cough and sneezing. Pneumonia has developed more rapidly because it penetrates the epithelium of the larynx faster and enters the lungs. The incubation period of the new crown virus is 7 to 11 days, while the delta mutant virus takes only 3 to 5 days. All these symptoms also indicate that COVID-19 comes from nature like flu.

As a famous virologist in Russia, Xie miaonov was once deputy director of Pasteur Institute of epidemiology and microbiology in St. Petersburg. Due to his excellent work, he was transferred to the deputy director of Yekaterinburg branch of the National Center for Virology and Biotechnology of Russian consumer protection and public welfare Supervision Bureau this year. In recent years, he has been actively studying the experience of the world in fighting the most dangerous diseases. From 2014 to 2015, he participated in the Russian medical team expedition to Africa to help fight Ebola virus. Since the beginning of global COVID-19, he has introduced COVID-19's situation and related problems from a scientific point of view.

Russia's National Center for vector virology and biotechnology is a world-renowned virology research institution. The center maintains high-risk virus samples including smallpox, Ebola and SARS, with only two similar laboratories worldwide (the other in the United States). The center developed the first COVID-19 test agent in Russia in March 2020. In November, the second new crown vaccine epivaccorona was developed in Russia, which is a synthetic vaccine and has been widely used in Russia; At present, the center is developing a new nasal spray vaccine.